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Symbol
Name
ID

Plcb1
phospholipase C, beta 1
MGI:97613

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Spasticity	Hypsarrhythmia	Hyperreflexia	Epileptic encephalopathy	Developmental regression	Bilateral tonic-clonic seizure	Focal-onset seizure	Epileptic spasm	Tonic seizure
Disease(s) Associated with PLCB1
developmental and epileptic encephalopathy 12

Mouse Phenotypes		increased susceptibility to pharmacologically induced seizures	convulsive seizures	abnormal brain size	loss of hippocampal neurons	abnormal excitatory postsynaptic currents	decreased prepulse inhibition
Availability	Mouse Genotype		convulsive seizures	abnormal brain size	loss of hippocampal neurons	abnormal excitatory postsynaptic currents	decreased prepulse inhibition
	Plcb1^{Tg(LGB)56Mbal}/Plcb1^{Tg(LGB)56Mbal}
	Plcb1^tm1Hssh/Plcb1^tm1Hssh

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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